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AM-1220
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Synonyms: [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-methanone

Technical Information
Formal Name: [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-methanone
CAS Number: 137642-54-7
Molecular Formula: C26H26N2O
Formula Weight: 382.5
Purity:
98%
Formulation: A
crystalline solid.
Solubility: DMF: 20 mg/ml
DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml
DMSO: 5 mg/ml
Ethanol: 0.15 mg/ml
Methanol: 1 mg/ml

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AM1220 is a potent synthetic cannabinoid (CB) with preference for the central CB1 receptor (Ki = 3.88 nM) over the CB2 receptor (Ki = 73.4 nM).1 The physiological actions and metabolism of AM1220 have not been characterized.



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Product Citations
Cho, B., Cho, H.S., Kim, J., et al. Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair. Forensic Sci. Int. 306, 110058 (2020).
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