RCSHOPERS.COM SHOP

0
buy am-2201 online
Buy AM2201 online at rcshopers.com
Buy JWH-018 online at rcshopers.com
  • buy jwh-018 online
AM2201
$210
Technical Information

Formal Name: 1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone

CAS Number: 3250704-05-10

Formula Weight: 359.4

Purity:
98%
Formulation: A neat solid.

Solubility:
Dichloromethane: 20 mg/ml
DMF: 20 mg/ml
DMSO: 20 mg/ml
Ethanol: 5 mg/ml
Molecular Formula: C24H22FNO.
PRODUCT DESCRIPTION

AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.1 AM2201 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

AM-2201 is a synthetic cannabinoid that acts as a potent agonist at cannabinoid receptors and its abuse has increased. However, there are no reports of the inhibitory effect of AM-2201 on human cytochrome P450 (CYP) or uridine 5′-diphospho-glucuronosyltransferase (UGT) enzymes. We evaluated the inhibitory effect of AM-2201 on the activities of eight major human CYPs (1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4) and six major human UGTs (1A1, 1A3, 1A4, 1A6, 1A9, and 2B7) enzymes in pooled human liver microsomes using liquid chromatography–tandem mass spectrometry to investigate drug interaction potentials of AM-2201. AM-2201 potently inhibited CYP2C9-catalyzed diclofenac 4′-hydroxylation, CYP3A4-catalyzed midazolam 1′-hydroxylation, UGT1A3-catalyzed chenodeoxycholic acid 24-acyl-glucuronidation, and UGT2B7-catalyzed naloxone 3-glucuronidation with IC50 values of 3.9, 4.0, 4.3, and 10.0 µM, respectively, and showed mechanism-based inhibition of CYP2C8-catalyzed amodiaquine N-deethylation with a Ki value of 2.1 µM. It negligibly inhibited CYP1A2, CYP2A6, CYP2B6, CYP2C19, CYP2D6, UGT1A1, UGT1A4, UGT1A6, and UGT1A9 activities at 50 μM in human liver microsomes. These in vitro results indicate that AM-2201 needs to be examined for potential pharmacokinetic drug interactions in vivo due to its potent inhibition of CYP2C8, CYP2C9, CYP3A4, UGT1A3, and UGT2B7 enzyme activities.


TIMOTHY W
October 04, 2022
It was a great experience to order online from Rcshopers.com. I have been trying to get some research chemicals for my school project locally but, it wasnt easy for me. Its not easy to find research chemicals vendor online, this was a great challenge for me. A friend told me about Rcshopers.com and I took the initiative to try them out. I was surprised at how fast their delivery process was and I got exactly what I wanted. I was relieved to know that, now I can now get my stuffs from Rcshopers.com, with ease.
MARIE W
September 13, 2023
Well sourced quality and variety products!
Good selection of herbs incense and bath salts. The shipping process was top notch took only 3 days and I got my package with exactly what I ordered. I would definitely use them again and I would recommend them highly!
RELATED PRODUCTS
buy JWH-073 online at Rcshopers.com
JWH-073
JWH-073 Powder:
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a partial agonist at both the CB and CB cannabinoid receptors.

IGeneral description. A synthetic cannabinoid found in several versions of the herbal mixture “Spice,” JWH-073 is considerably more potent than natural.Our JWH 073 is confirmed by NMR. Order now can get a discount! ... Catalog No. BCC1674----Order now to get a substantial discount! ... Inquiry Online. Related

Buy JWH-073 Online:
This product has been formulated as an exempt preparation which meets criteria established by the US DEA; Possession of a DEA Controlled Substance. Order JWH-073 online at Rcshopers.com, we are dealers of research chemicals such as JWH-073.
$200
buy JWH-122 online at rcshopers.com
JWH-122
JWH-122 is a synthetic cannabimimetic that was discovered by John W. Huffman. It is a methylated analogue of JWH-018. It has a K? of 0.69 nM at CB and 1.2 nM at CB. Purchase online CAS Number 1651833-50-9 - Rcshopers.com Chemical - JWH 122-d9. High Quality CRMs, Reference Materials, Proficiency Testing & More at LGC

JWH-122 4-Hydroxypentyl metabolite solution. Simplify Your Research needs with accurate and reliable results with Rcshopers.com. 30,000+ products. Advanced Search. Peer-reviewed papers. Research Protocols. Services: MSDS Authoring, Regulatory Compliance, Product Development.

he highest measured concentrations were 70 pg/mg of JWH-018, 260 pg/mg of JWH-122, and 950 pg/mg of JWH-210.
$210

a-PVP
Buy alpha-pvp a-pvp, buy Flakka, buy A-pvp research chemicals drugs with Bitcoin from Rcshopers.com online without license. Rcshopers are dealers of research chemicals such as a-PVP, buy a-pvp online with credit cards.
alpha-Pyrrolidinopentiophenone:

a-Pyrrolidinopentiophenone is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug. Colloquially, it is sometimes called flakka. a-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane. a-PVP is one of our best seller research chemicals online today.

Buy a-PVP Online:
We have been dealers of a-pvp research chemical for decade now.
$220
buy AM-1220 online Rcshopers.com
AM-1220
AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.1 AM2201 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
The success of synthetic cannabinoids is due to several reasons: major psychoactive effects, affordable price, purchase through the Internet.
Product Citations
Cho, B., Cho, H.S., Kim, J., et al. Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair. Forensic Sci. Int. 306, 110058 (2020).
Good news for research chemicals consumers in USA and around the world. Rcshopers.com is pleased to inform its costumers about our new products such AM-1220 with high quality and an affordable price.
$215